Table 1 Distribution of CYP1A1 MspI and exon7 genotypes among lung cancer cases and controls included in this meta-analysis
From: CYP1A1 MspI and exon7 gene polymorphisms and lung cancer risk: An updated meta-analysis and review
First author-year | Ethnicity(country of origin) | Total sample size (case/control) | Lung cancer cases of MspI genotype | Controls of MspI genotype | Lung cancer cases of exon7 genotype | Controls of exon7 genotype | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Type B | Type C | Type A | Type B | Type C | Type A | Ile/Val | Val/Val | Ile/Ile | Ile/Val | Val/Val | Ile/Ile |
Kawajiri K-1990 | Asia(Japan) | 68/104 | 28 | 16 | 24 | 42 | 11 | 51 | NA | NA | NA | NA | NA | NA |
Tefre T-1991 | Caucasian(Norway) | 221/212 | 47 | 2 | 172 | 43 | 2 | 167 | NA | NA | NA | NA | NA | NA |
Hirvonen A-1992 | Caucasian(Finnish) | 87/121 | 22 | 0 | 65 | 24 | 2 | 95 | NA | NA | NA | NA | NA | NA |
Shields PG-1993 | Mixed populations | 56/48 | 11 | 2 | 43 | 12 | 3 | 33 | NA | NA | NA | NA | NA | NA |
Nakachi K-1993 | Asia(Japan) | 31/127 | 7 | 13 | 11 | 55 | 11 | 61 | 11 | 6 | 14 | 44 | 4 | 79 |
Alexandrie AK-1994 | Caucasian(Sweden) | 296/329 | 44 | 4 | 248 | 52 | 1 | 276 | 16 | 0 | 280 | 23 | 0 | 306 |
Kelsey K.T -1994 | Mixed(African Americans) | 72/97 | 11 | 1 | 60 | 21 | 2 | 74 | NA | NA | NA | NA | NA | NA |
Cantlay AM-1995 | Caucasian(Edinburgh) | 129/281 | NA | NA | NA | NA | NA | NA | 21 | 2 | 106 | 33 | 3 | 245 |
Kihara M-1995 | Asia(Japan) | 97/258 | 45 | 16 | 36 | 105 | 41 | 112 | 31 | 5 | 59 | 98 | 14 | 143 |
Xu XP-1996 | Caucasian(USA) | 207/238 | 35 | 2 | 170 | 48 | 2 | 233 | NA | NA | NA | NA | NA | NA |
Garcia-ClosaM-1997 | Mixed populations | 416/446 | 75 | 4 | 337 | 73 | 4 | 369 | NA | NA | NA | NA | NA | NA |
Ishibe N-1997 | Mixed(Mexican and African) | 171/295 | 68 | 12 | 91 | 106 | 35 | 154 | 31 | 7 | 132 | 70 | 20 | 204 |
Hong YS-1998 | Asia(Korean) | 85/63 | 45 | 6 | 34 | 31 | 3 | 29 | 68 | 1 | 16 | 60 | 1 | 2 |
Taioli E-1998 | Mixed populations | 105/307 | 30 | 9 | 59 | 101 | 18 | 170 | 8 | 1 | 94 | 18 | 0 | 272 |
Sugimura H-1998 | Asia(Japan) | 247/185 | NA | NA | NA | NA | NA | NA | 94 | 28 | 125 | 84 | 7 | 94 |
Le Marchand L-1998 | Mixed populations | 341/456 | 121 | 35 | 183 | 160 | 44 | 250 | 68 | 6 | 263 | 105 | 13 | 335 |
Xue KX-1999 | Asia(china) | 103/131 | NA | NA | NA | NA | NA | NA | 31 | 18 | 54 | 36 | 11 | 36 |
Hu YL-1999 | Asia(china) | 59/132 | 22 | 15 | 22 | 76 | 22 | 34 | 33 | 7 | 19 | 102 | 9 | 21 |
London SJ-2000 | Asia(China) | 214/669 | NA | NA | NA | NA | NA | NA | 39 | 8 | 167 | 130 | 27 | 512 |
Dresler CM-2000 | Caucasian(USA) | 158/149 | Â | 37* | 121 | Â | 17* | 132 | NA | NA | NA | NA | NA | NA |
Song N-2001 | Asia(China) | 217/404 | 129 | 28 | 60 | 175 | 56 | 173 | 130 | 9 | 78 | 181 | 13 | 210 |
Ratnasinghe D-2001 | Caucasian(USA) | 282/324 | NA | NA | NA | NA | NA | NA | 36 | 3 | 243 | 48 | 3 | 273 |
Quinones L-2001 | Caucasians(Chile) | 60/174 | 29 | 10 | 16 | 38 | 16 | 86 | 35 | 10 | 15 | 52 | 14 | 54 |
Chen S-2001 | Asia(china) | 106/106 | NA | NA | NA | NA | NA | NA | 38 | 10 | 58 | 33 | 3 | 70 |
Xue KX-2001 | Asia(china) | 106/106 | NA | NA | NA | NA | NA | NA | 38 | 10 | 58 | 33 | 3 | 33 |
Yin LH-2002 | Asia(china) | 84/84 | 34 | 13 | 37 | 38 | 18 | 28 | NA | NA | NA | NA | NA | NA |
Zhou XW-2002 | Asia(china) | 92/98 | 43 | 15 | 34 | 34 | 13 | 51 | 66 | 11 | 15 | 65 | 6 | 65 |
Cai XL-2003 | Asia(china) | 91/138 | 23 | 36 | 32 | 46 | 39 | 53 | NA | NA | NA | NA | NA | NA |
Kiyohara C-2003 | Asia(Japan) | 158/259 | 64 | 17 | 77 | 115 | 28 | 116 | NA | NA | NA | NA | NA | NA |
Taioli E-2003 | Mixed populations | 109/424 MspI 110/707exon7 | 20 | 5 | 84 | 75 | 4 | 345 | 16 | 1 | 93 | 70 | 2 | 635 |
Wang J-2003 | Asia(china) | 162/181 | 76 | 22 | 64 | 78 | 38 | 65 | NA | NA | NA | NA | NA | NA |
Dialyna IA-2003 | Caucasians (Greek) | 122/178 | 28 | 5 | 89 | 45 | 3 | 130 | NA | NA | NA | NA | NA | NA |
Dong CT-2004 | Asia(china) | 82/91 | NA | NA | NA | NA | NA | NA | 36 | 18 | 28 | 32 | 10 | 32 |
Gu YF-2004 | Asia(china) | 180/224 | Â | 129 * | 51 | Â | 138* | 86 | NA | NA | NA | NA | NA | NA |
Liang GY-2004 | Asia(china) | 152/152 | 82 | 20 | 50 | 71 | 11 | 70 | NA | NA | NA | NA | NA | NA |
Chen SD-2004 | Asia(china) | 58/62 | 15 | 23 | 20 | 20 | 18 | 24 | NA | NA | NA | NA | NA | NA |
Yang XR-2004 | Asia(China) | 200/144 | NA | NA | NA | NA | NA | NA | 96 | 11 | 90 | 39 | 7 | 98 |
Sobti RC-2004 | Asia(India) | 100/76 | 45 | 6 | 49 | 29 | 5 | 42 | 67 | 29 | 4 | 53 | 15 | 8 |
Wenzlaff AS-2005 | Caucasian(USA) | 128/181 | 35 | 0 | 93 | 30 | 4 | 116 | 5# | Â | 124 | 14# | Â | 134 |
Wrensch MR-2005 | Mixed populations | 371/944 MspI 363/930exon7 | Â | 166* | 205 | Â | 472* | 472 | Â | 64# | 302 | Â | 219# | 711 |
Ng DP-2005 | Asia(Singapore) | 126/162 | 61 | 22 | 41 | 87 | 19 | 56 | 39 | 13 | 74 | 63 | 7 | 91 |
Larsen EJ-2005 | Caucasians(Australia) | 1050/581 | NA | NA | NA | NA | NA | NA | 84 | 8 | 958 | 27 | 2 | 552 |
Raimondi S-2005 | Caucasians | 165/519 MspI 175/723exon7 | Â | 43* | 122 | Â | 102* | 417 | Â | 32# | 143 | Â | 67# | 656 |
Raimondi S-2005-2 | Asians | 46/138 MspI 60/212 exon7 | Â | 28* | 18 | Â | 95* | 43 | Â | 30# | 30 | Â | 96# | 116 |
Sreeja L-2005 | Asia(Indian) | 146/146 | 53 | 22 | 71 | 45 | 8 | 93 | NA | NA | NA | NA | NA | NA |
Adonis M-2005 | Mixed populations | 57/103 | 31 | 11 | 15 | 33 | 26 | 44 | NA | NA | NA | NA | NA | NA |
Belogubova-2006 | Caucasians (Russian) | 141/450 | 35 | 2 | 104 | 90 | 3 | 357 | NA | NA | NA | NA | NA | NA |
Li DR-2006 | Asia(china) | 150/152 | NA | NA | NA | NA | NA | NA | 104 | 14 | 32 | 105 | 8 | 105 |
Pisani P-2006 | Asia(Thailand) | 211/408 | 87 | 55 | 26 | 155 | 78 | 53 | 79 | 10 | 78 | 129 | 23 | 135 |
Yang MH-2007 | Asia(Korea) | 314/349 | NA | NA | NA | NA | NA | NA | 116 | 16 | 182 | 111 | 18 | 220 |
Tao WH-2007 | Asia(china) | 47/94 | 19 | 4 | 24 | 37 | 14 | 43 | NA | NA | NA | NA | NA | NA |
Cote ML-2007 | Mixed populations | 354/440 | 80 | 5 | 269 | 95 | 6 | 339 | 19 | 0 | 326 | 34 | 6 | 400 |
Xia Y-2008 | Asia(china) | 58/116 | 36 | 5 | 17 | 58 | 18 | 40 | NA | NA | NA | NA | NA | NA |
Qi XS-2008 | Asia(china) | 53/72 | 29 | 7 | 17 | 38 | 11 | 23 | NA | NA | NA | NA | NA | NA |
Yoon KA-2008 | Asia(Korea) | 213/213 | NA | NA | NA | NA | NA | NA | 76 | 10 | 127 | 87 | 10 | 116 |
Gallegos-Arreola-2008 | Mixed populations | 222/248 | NA | NA | NA | NA | NA | NA | 91 | 40 | 91 | 104 | 11 | 133 |
Shah PP-2008 | Asia(India) | 200/200 | Â | 94* | 106 | Â | 63* | 137 | Â | 67# | 133 | Â | 44# | 156 |
Kumar M-2009 | Asia(India) | 93/253 | NA | NA | NA | NA | NA | NA | 17 | 3 | 73 | 40 | 3 | 210 |
Cote ML-2009 | Mixed populations | 502/523 | 109 | 14 | 373 | 110 | 7 | 402 | 38 | 0 | 464 | 32 | 2 | 489 |
Honma HN-2009 | Mixed populations | 200/264 | 76 | 11 | 113 | 94 | 9 | 161 | NA | NA | NA | NA | NA | NA |
Klinchid J-2009 | Asia(Thailand) | 85/82 | Â | 66* | 19 | Â | 66* | 16 | Â | 47# | 33 | Â | 42# | 38 |
Timofeeva MN-2009 | Caucasians (German) | 619/1264 | NA | NA | NA | NA | NA | NA | 248 | 61 | 260 | 545 | 117 | 585 |
Shaffi SM-2009 | Asia(India) | 109/163 | Â | 81* | 28 | Â | 85* | 78 | NA | NA | NA | NA | NA | NA |
Jin Y-2010 | Asia(China) | 124/154 | Â | 71* | 79 | Â | 70* | 80 | NA | NA | NA | NA | NA | NA |
Wright CM-2010 | Caucasians (Australian) | 1040/784 | 219 | 24 | 797 | 128 | 10 | 646 | 103 | 8 | 929 | 40 | 3 | 741 |