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Table 4 Correlation between TFPI-2 status and and AI, PI, VEGF and MVD during malignant grading

From: Reduced expression of tissue factor pathway inhibitor-2 contributes to apoptosis and angiogenesis in cervical cancer

 

AI

PI

VEGF

MVD(mean ± SD)

 

TFPI-2

(+)

TFPI-2

(-)

TFPI-2

(+)

TFPI-2

(-)

TFPI-2

(+)

TFPI-2

(-)

TFPI-2

(+)

TFPI-2

(-)

Normal

0a

-

11.3a

-

0.25a

-

30.5 ± 12.5a

-

CIN I

0.12a, b

-

20.1a, b

-

0.38a, b

-

36.1 ± 7.9a, b

-

CIN II/III

1.13a, c

-

50.8c, d

-

0.59a, b

-

42.6 ± 24.3a, b

-

ICC

2.41

1.8

57.5

64.7

1.2

2.2

63.5 ± 19.3

69.8 ± 21.0

P*

 

0.001

 

0.054

 

< 0.001

 

0.033

  1. ap < 0.001 when compared to ICC; bp > 0.05 when compared to normal cervix;and cP < 0.001 when CIN I compared to CIN II/III; dP = 0.005 when CIN II/III compared to ICC; P* when TFPI-2-negative compared to TFPI-2-positive. The TFPI-2 positive results of +,++,+++ and ++++ were merged into one group.
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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