Figure 2
From: ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL
Bcl-2 and Bcl-xL are overexpressed in MDA-MB-231R cells. (A) Western blot analysis showed that the anti-apoptotic proteins Bcl-2 and Bcl-xL are overexpressed in the MDA-MB-231R cells compared with MDA-MB-231 cells. Lane 1, MDA-MB-231 cells; lane 2, MDA-MB-231R cells. (B) RT-PCR analysis further confirmed an overexpression of Bcl-2 and Bcl-xL in the MDA-MB-231R cells. Lane 1, marker; lane 2, MDA-MB-231cells; lane 3, MDA-MB-231R cells.