Clear cell carcinoma of the ovary: Is there a role of histology-specific treatment?

Table 1 Rates of lymph node metastasis in early-staged clear cell carcinoma and serous adenocarcinoma

author	year	number of patients	pT stage	metastatic rate
clear cell carcinoma
Di Re[2]	1989	11	pT1	9% (1/11)
Petru[3]	1994	2	pT1	0% (0/2)
Onda[4]	1996	16	pT1/2	31% (5/16)
Baiocchi[5]	1998	21	pT1	5% (1/21)
Suzuki[6]	2000	9	pT1	11% (1/9)
Sakuragi[7]	2000	23	pT1/2	17% (4/23)
Negishi[8]	2004	46	pT1	12% (5/42)
Negishi[8]	2004	46	pT2	75% (3/4)
Takano[9]	2006	173	pT1a	9% (3/36)
			pT1c	7% (7/99)
			pT2	13%(5/38)
Harter[10]	2007	7	pT1	0% (0/7)
Desteli[11]	2010	4	pT1	0% (0/4)
Nomura[12]	2010	36	pT1/2	6% (2/36)
Subtotal		348		11%(37/348)
Serous cystadenocarcinoma
Di Re[2]	1989	40	pT1	28% (11/40)
Petru[3]	1994	21	pT1	38% (8/21)
Onda[4]	1996	21	pT1/2	33% (7/21)
Baiocchi[5]	1998	106	pT1	26% (27/106)
Suzuki[6]	2000	13	pT1	31% (4/13)
Sakuragi[7]	2000	25	pT1/2	8% (2/25)
Morice[13]	2003	26	pT1	31% (8/26)
Negishi[8]	2004	35	pT1	4% (1/24)
Negishi[8]	2004	35	pT2	36% (4/11)
Harter[10]	2007	13	pT1	15% (2/13)
Desteli[11]	2010	7	pT1	14% (1/7)
Nomura[12]	2010	12	pT1/2	50% (6/12)
Subtotal		319		25%(81/319)

ISSN: 1756-9966