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Table 3 ORs of ≥ G2 fibrosis or fat necrosis for different polymorphisms and their combination

From: SNPs in DNA repair or oxidative stress genes and late subcutaneous fibrosis in patients following single shot partial breast irradiation

Polymorphisms

Genotype

≥ G2 fibrosis

or fat

necrosis

OR

(95% CI)

p-value (*)

p-value (§)

XRCC1 (Arg399Gln)

AA

45%

1

  
 

aa/Aa

54%

1.41 (0.44-4.58)

0.514

0.599

XRCC3( A4541G)

aa/Aa

44%

1

  
 

AA

53%

1.43 (0.45-4.71)

0.494

0.596

XRCC3(C18067T)

AA/Aa

51%

1

  
 

aa

33%

0.49 (0.04-3.75)

0.413

0.670

GSTP1

AA

38%

1

  
 

aa/Aa

64%

2.9 (0.88-10.14)

0.047

0.064

RAD51

AA

48%

1

  
 

aa/Aa

67%

NA #

0.9751

0.6115

  1. Abbreviations: (*) Chi-squared, (§) Fisher's exact Test, #: not applicable due to the limited number of events