Table 2 Genotype and allele frequencies of the five SNPs between cases and controls
Polymorphisms | Controls (n = 595) (%) | CRC (n = 313) (%) | Adjusted OR (95% CI) | p |
|---|---|---|---|---|
rs1016343 | Â | Â | Â | Â |
CC | 227(38.1) | 117(37.4) | 1.0(ref) | Â |
CT | 276(46.4) | 156(49.8) | 1.33(0.82-2.14) | 0.25 |
TT | 92(15.5) | 40(12.8) | 1.13(0.83-1.55) | 0.44 |
C | 730(61.3) | 390(62.3) | 1.0(ref) | Â |
T | 460(38.7) | 236(37.7) | 1.14(0. 92–1.41) | 0.24 |
rs13252298 | Â | Â | Â | Â |
AA | 264(44.4) | 166(53.0) | 1.0(ref) | Â |
AG | 270(45.4) | 121(38.7) | 0.67(0.49-0.91) | 0.01 |
GG | 61(10.2) | 26(8.3) | 0.64(0.38-1.09) | 0.10 |
A | 798(67.1) | 453(72.4) | 1.0(ref) | Â |
G | 392(32.9) | 173(27.6) | 0.75(0.60-0.94) | 0.01 |
rs7007694 | Â | Â | Â | Â |
TT | 362(60.8) | 184(58.8) | 1.0(ref) | Â |
CT | 208(35.0) | 107(34.2) | 1.04(0.76-1.42) | 0.80 |
CC | 25(4.2) | 22(7.0) | 1.60(0.85-3.03) | 0.15 |
T | 932(78.3) | 475(75.9) | 1.0(ref) | Â |
C | 258(21.7) | 151(24.1) | 1.15(0.90-1.46) | 0.27 |
rs16901946 | Â | Â | Â | Â |
AA | 338(56.8) | 175(55.9) | 1.0(ref) | Â |
AG | 232(39.0) | 117(37.4) | 0.96(0.71-1.31) | 0.80 |
AG/GG | 257(43.2) | 138(44.1) | 1.03(0.77-1.38) | 0.85 |
A | 908(76.3) | 467(74.6) | 1.0(ref) | Â |
G | 282(23.7) | 159(25.4) | 1.10(0.86-1.39) | 0.45 |
rs1456315 | Â | Â | Â | Â |
AA | 294(49.4) | 167(53.4) | 1.0(ref) | Â |
AG | 262(44.0) | 119(38.0) | 0.66(0.48-0.90) | 0.01 |
GG | 39(6.6) | 27(8.6) | 1.09(0.62-1.91) | 0.78 |
A | 850(71.4) | 453(72.4) | 1.0(ref) | Â |
G | 340(28.6) | 173(27.6) | 0.86(0.70-1.08) | 0.18 |