|
Polymorphisms
|
Controls (n = 595) (%)
|
CRC (n = 313) (%)
|
Adjusted OR (95% CI)
|
p
|
|---|
|
rs1016343
| | | | |
|
CC
|
227(38.1)
|
117(37.4)
|
1.0(ref)
| |
|
CT
|
276(46.4)
|
156(49.8)
|
1.33(0.82-2.14)
|
0.25
|
|
TT
|
92(15.5)
|
40(12.8)
|
1.13(0.83-1.55)
|
0.44
|
|
C
|
730(61.3)
|
390(62.3)
|
1.0(ref)
| |
|
T
|
460(38.7)
|
236(37.7)
|
1.14(0. 92–1.41)
|
0.24
|
|
rs13252298
| | | | |
|
AA
|
264(44.4)
|
166(53.0)
|
1.0(ref)
| |
|
AG
|
270(45.4)
|
121(38.7)
|
0.67(0.49-0.91)
|
0.01
|
|
GG
|
61(10.2)
|
26(8.3)
|
0.64(0.38-1.09)
|
0.10
|
|
A
|
798(67.1)
|
453(72.4)
|
1.0(ref)
| |
|
G
|
392(32.9)
|
173(27.6)
|
0.75(0.60-0.94)
|
0.01
|
|
rs7007694
| | | | |
|
TT
|
362(60.8)
|
184(58.8)
|
1.0(ref)
| |
|
CT
|
208(35.0)
|
107(34.2)
|
1.04(0.76-1.42)
|
0.80
|
|
CC
|
25(4.2)
|
22(7.0)
|
1.60(0.85-3.03)
|
0.15
|
|
T
|
932(78.3)
|
475(75.9)
|
1.0(ref)
| |
|
C
|
258(21.7)
|
151(24.1)
|
1.15(0.90-1.46)
|
0.27
|
|
rs16901946
| | | | |
|
AA
|
338(56.8)
|
175(55.9)
|
1.0(ref)
| |
|
AG
|
232(39.0)
|
117(37.4)
|
0.96(0.71-1.31)
|
0.80
|
|
AG/GG
|
257(43.2)
|
138(44.1)
|
1.03(0.77-1.38)
|
0.85
|
|
A
|
908(76.3)
|
467(74.6)
|
1.0(ref)
| |
|
G
|
282(23.7)
|
159(25.4)
|
1.10(0.86-1.39)
|
0.45
|
|
rs1456315
| | | | |
|
AA
|
294(49.4)
|
167(53.4)
|
1.0(ref)
| |
|
AG
|
262(44.0)
|
119(38.0)
|
0.66(0.48-0.90)
|
0.01
|
|
GG
|
39(6.6)
|
27(8.6)
|
1.09(0.62-1.91)
|
0.78
|
|
A
|
850(71.4)
|
453(72.4)
|
1.0(ref)
| |
|
G
|
340(28.6)
|
173(27.6)
|
0.86(0.70-1.08)
|
0.18
|
- OR: odds ratio; CI: confidence interval; Ref: reference.
