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Table 3 Stratified analyses of lncRNA PRNCR1 polymorphisms with clinical features in patients with CRC (minor allele vs. major allele)

From: Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer

Polymorphisms

Adjusted OR for age and gender (95% CI)/p

Tumor size (≥5 cm)

Differentiated status (poorly)

Clinical stage (III-IV)

Metastasis (yes)

rs1016343C/T

0.82(0.59-1.13)/0.22

1.05(0.72-1.55)/0.79

1.07(0.77-1.49)/0.70

1.27(0.91-1.78)/0.16

rs13252298A/G

1.07(0.75-1.52)/0.72

1.21(0.80-1.82)/0.37

0.85(0.59-1.21)/0.36

0.76(0.53-1.10)/0.15

rs7007694T/C

0.74(0.51-1.08)/0.11

0.46(0.28-0.77)/0.003

1.04(0.71-1.51)/0.85

1.11(0.76-1.62)/0.59

rs16901946A/G

0.84(0.59-1.22)/0.36

0.59(0.37-0.94)/0.03

1.09(0.76-1.58)/0.64

1.26(0.87-1.83)/0.22

rs1456315A/G

1.56(1.10-2.23)/0.01

1.54(1.03-2.31)/0.04

1.16(0.81-1.66)/0.43

1.06(0.73-1.52)/0.77

  1. CRC: colorectal cancer; OR: odds ratio; CI: confidence interval.
  2. The smaller size, well differentiated status, clinical stage I-II, and the ones without metastasis were made as references, respectively.