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Table 3 Univariate and multivariate Cox regression analyses of recurrence-free survival in 100 HCC patients following LT

From: Decrease expression of microRNA-20a promotes cancer cell proliferation and predicts poor survival of hepatocellular carcinoma

Parameter

Univariate analysis

Multivariable analysis

HR

95% CI

P-value

HR

95% CI

P-value

Age

0.849

0.713-1.275

0.746

-

-

-

Gender

1.092

0.534-2.801

0.331

-

-

-

HBV infection

0.583

0.228-1.144

0.192

-

-

-

Cirrhosis

0.746

0.434-1.204

0.493

-

-

-

Tumor size

1.632

1.031-1.918

0.011*

1.253

1.123-1.792

0.014*

Tumor stage (III)

1.876

1.319-2.592

0.026*

1.348

0.935-1.813

0.365

Histologic grade (G3/G1-2)

3.731

1.774-5.103

0.024*

2.931

1.526-3.858

0.079

Milan criteria (out)

2.182

1.962-6.212

0.018*

1.935

1.332-3.563

0.156

AFP >400 (ng/ml)

1.939

1.638-4.809

0.012*

2.235

1.771-4.595

0.028*

Micro-vascular invasion

4.017

3.137-7.583

0.009*

3.643

2.964-6.927

0.012*

miR-20a (low)

4.591

2.933-8.457

0.015*

4.281

3.316-6.741

0.013*

  1. Note: *statistically significant difference.
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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