Tau protein as a potential predictive marker in epithelial ovarian cancer patients treated with paclitaxel/platinum first-line chemotherapy

Table 6 Association between Tau expression and response to chemotherapy in patients with measurable target lesions according to RECIST scale (n=46)

Response to chemotherapy according to RECIST	Negative Tau expression (n=11)		Positive Tau expression (n=35)		Mann – Whitney test U
Response to chemotherapy according to RECIST	n	%	n	%	Z	P
OR (CR+PR)	10	90.9%	19	54.3%	2.17	0.0299
SD+PD	1	9.1%	16	45.7%	2.17	0.0299
CR	10	90.9%	18	51.4%	2.09	0.0362
PR	-	-	1	2.9%
SD	-	-	9	25.7%
PD	1	9.1%	7	20%

Abbreviations: OR – objective response, CR – complete response, PR- partial response, SD – stable disease, PD – progression disease.

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