Figure 4From: Inhibition of ADAM-17 more effectively down-regulates the Notch pathway than that of γ-secretase in renal carcinomaThe effect of Marimastat and DAPT on apoptosis of renal carcinoma cells. A–E: Flow cytometry was performed after Annexin-PI staining to observe the 786-O apoptosis rate after treatment with either of the two inhibitors at two doses. 1 μmol/L DAPT (A) and Marimastat (B); 3 μmol/L DAPT (C) and Marimastat (D); DMSO control (E).Back to article page