Figure 2

Representative the expression of Bmi1, CD44, CD133, Sox2, Nanog, OCT4 and Msi2 in normal lung, benign lesion and lung cancer. (A) Nuclear staining of Bmi1 is expressed (red arrows) in normal lung, benign fibroma of lung and squamous cell carcinomas. (B) Membranous staining of CD44 in normal lung, benign fibroma of lung and squamous cell carcinomas. (C) Membranous and cytoplastic staining of CD133 in normal bronchial epithelium cells and squamous cell carcinomas, negative immunostaining signal of CD133 in benign fibroma of lung. (D) Nuclear staining of Sox2 in normal bronchial epithelium cells, squamous metaplasia and squamous cell carcinomas. (E) Cytoplastic and nuclear staining of Msi2 in normal bronchial epithelium cells, squamous metaplasia and squamous cell carcinomas. (F) Negative immunostaining signal of Nanog in normal lung, cytoplastic staining of Nanog in squamous metaplasia and squamous cell carcinomas. (G). Negative immunostaining signal of OCT4 in normal lung and tuberculosis, nuclear staining of OCT4 in small cell lung carcinomas. All images were taken at 400× magnification.