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Table 3 Mutational analysis of K-ras, p53 and EGFR in NSCLC patients with E2A-PBX1 fusion transcripts and NSCLC cell lines

From: Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer

# E2A-PBX1 k-Kras codon 12 p53 EGFR Age Gender Race Smoking status Stage Histology
2 +     67 M Middle Eastern S IIIB Adc
12 +     72 F Hispanic S IB Adc
14 +     66 F Caucasian S IIB Adc
18 + G12V    78 F Caucasian S IB Adc
20 + G12C    63 F Caucasian S IV Adc
1 +     71 F Caucasian S IA AIS
3 +     41 M Caucasian S IV AIS
8 +     59 M Caucasian NS IB AIS
9 +     73 F Caucasian S IIIB AIS
11 +     84 M Caucasian S IA AIS
13 +     61 F South Asian NS IB AIS
21 +     82 F Caucasian S IA AIS
22 +     48 F East Asian NS IB AIS
16 +   G245S   63 F Caucasian S IA AIS
7 +   V272M L858R 73 F Caucasian S IIIB AIS
6 + G12C    68 M Southeast Asian S IIIA AIS
10 + G12C    71 M Hispanic S IA AIS
17 + G12C    67 F Caucasian S IB AIS
19 + G12C    79 F Caucasian S IIA AIS
5 + G12A    54 F Caucasian S IIIB AIS
15 + G12V exon 7(FS)   67 F Caucasian S IV AIS
4 +     39 M Caucasian NS IB LCC
23 + ND 72 F Caucasian S IA AIS   
Cell line           
A549 + G12S    58 M Caucasian    Adc
A427 + G12D    52 M Caucasian    Adc
H441 - G12V R158L    M     Adc
H838 -     59 M Caucasian S IIIB Adc
H1975 -   R273H L858R, T790M   F   NS   Adc
H1650 -    Exon 19 deletion 27 M Caucasian S IIIB Adc
H322 -   R248L   52 M Caucasian    BAC
H358 - G12C Null    M Caucasian    BAC
H1666 +     50 F Caucasian NS III? BAC
H2170 -   R158G    M   NS   Sqc
H1703 -   E285K   54 M Caucasian S I Sqc
H460 - Q61H     M     LCC
H1299 -   Null   43 M Caucasian    LCC
  1. FS: frame shift; M: male; F: female; S: smoker; NS: non-smoker; Adc: adenocarcinoma; AIS: adenocarcinoma in situ; BAC: brochioloalveolar carcinoma (histology information from ATCC still uses BAC); LCC: large cell carcinoma; Sqc: squamous carcinoma; ND: not determined.