Table 3 Mutational analysis of K-ras, p53 and EGFR in NSCLC patients with E2A-PBX1 fusion transcripts and NSCLC cell lines
From: Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer
# | E2A-PBX1 | k-Kras codon 12 | p53 | EGFR | Age | Gender | Race | Smoking status | Stage | Histology |
|---|---|---|---|---|---|---|---|---|---|---|
2 | + | 67 | M | Middle Eastern | S | IIIB | Adc | |||
12 | + | 72 | F | Hispanic | S | IB | Adc | |||
14 | + | 66 | F | Caucasian | S | IIB | Adc | |||
18 | + | G12V | 78 | F | Caucasian | S | IB | Adc | ||
20 | + | G12C | 63 | F | Caucasian | S | IV | Adc | ||
1 | + | 71 | F | Caucasian | S | IA | AIS | |||
3 | + | 41 | M | Caucasian | S | IV | AIS | |||
8 | + | 59 | M | Caucasian | NS | IB | AIS | |||
9 | + | 73 | F | Caucasian | S | IIIB | AIS | |||
11 | + | 84 | M | Caucasian | S | IA | AIS | |||
13 | + | 61 | F | South Asian | NS | IB | AIS | |||
21 | + | 82 | F | Caucasian | S | IA | AIS | |||
22 | + | 48 | F | East Asian | NS | IB | AIS | |||
16 | + | G245S | 63 | F | Caucasian | S | IA | AIS | ||
7 | + | V272M | L858R | 73 | F | Caucasian | S | IIIB | AIS | |
6 | + | G12C | 68 | M | Southeast Asian | S | IIIA | AIS | ||
10 | + | G12C | 71 | M | Hispanic | S | IA | AIS | ||
17 | + | G12C | 67 | F | Caucasian | S | IB | AIS | ||
19 | + | G12C | 79 | F | Caucasian | S | IIA | AIS | ||
5 | + | G12A | 54 | F | Caucasian | S | IIIB | AIS | ||
15 | + | G12V | exon 7(FS) | 67 | F | Caucasian | S | IV | AIS | |
4 | + | 39 | M | Caucasian | NS | IB | LCC | |||
23 | + | ND | 72 | F | Caucasian | S | IA | AIS | ||
Cell line | ||||||||||
A549 | + | G12S | 58 | M | Caucasian | Adc | ||||
A427 | + | G12D | 52 | M | Caucasian | Adc | ||||
H441 | - | G12V | R158L | M | Adc | |||||
H838 | - | 59 | M | Caucasian | S | IIIB | Adc | |||
H1975 | - | R273H | L858R, T790M | F | NS | Adc | ||||
H1650 | - | Exon 19 deletion | 27 | M | Caucasian | S | IIIB | Adc | ||
H322 | - | R248L | 52 | M | Caucasian | BAC | ||||
H358 | - | G12C | Null | M | Caucasian | BAC | ||||
H1666 | + | 50 | F | Caucasian | NS | III? | BAC | |||
H2170 | - | R158G | M | NS | Sqc | |||||
H1703 | - | E285K | 54 | M | Caucasian | S | I | Sqc | ||
H460 | - | Q61H | M | LCC | ||||||
H1299 | - | Null | 43 | M | Caucasian | LCC |