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Table 1 Peritumoral and intratumoral IL-17RE expression according to characteristics of 300 HCC patients

From: High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

Characteristics Peritumoral IL-17RE Intratumoral IL-17RE
   Low high p Low high p
   n = 176 n = 124   n = 221 n = 79  
Gender Male 144 109 0.197 187 66 0.857
  Female 32 15 34 13   
Age(years) ≤53 90 67 0.640 121 36 0.190
  >53 86 57 100 43   
ALT(U/L) ≤75 154 109 1.000 193 70 0.844
  >75 22 15 28 9   
AFP(ng/ml) >20 104 87 0.52 138 53 0.498
  ≤20 72 37   83 26  
Hepatitis history Yes 130 88 0.601 62 20 0.769
  No 46 36 159 59   
Cirrhosis Yes 155 110 1.000 199 66 0.152
  No 21 14 22 13   
Vascular invasion Yes 38 46 0.004 61 23 0.884
  No 138 78 160 56   
Encapsulation Yes 89 68 0.483 114 43 0.695
  No 87 56 107 36   
Number Single 155 108 0.859 196 67 0.425
  Multiple 21 16 25 12   
Size(cm) ≤5 122 72 0.50 145 49 0.585
  >5 54 52 76 30   
Differentiation I-II 128 92 0.793 166 54 0.299
  III-IV 48 32 55 25   
TNM stage I 129 73 0.012 150 52 0.780
  II-III 47 51 71 27   
  1. IL-17RE: interleukin-17receptor E; AFP: alpha fetoprotein; ALT, alanine aminotransferase; TNM, tumor-node-metastasis.