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Table 1 Peritumoral and intratumoral IL-17RE expression according to characteristics of 300 HCC patients

From: High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

Characteristics

Peritumoral IL-17RE

Intratumoral IL-17RE

  

Low

high

p

Low

high

p

  

n = 176

n = 124

 

n = 221

n = 79

 

Gender

Male

144

109

0.197

187

66

0.857

 

Female

32

15

34

13

  

Age(years)

≤53

90

67

0.640

121

36

0.190

 

>53

86

57

100

43

  

ALT(U/L)

≤75

154

109

1.000

193

70

0.844

 

>75

22

15

28

9

  

AFP(ng/ml)

>20

104

87

0.52

138

53

0.498

 

≤20

72

37

 

83

26

 

Hepatitis history

Yes

130

88

0.601

62

20

0.769

 

No

46

36

159

59

  

Cirrhosis

Yes

155

110

1.000

199

66

0.152

 

No

21

14

22

13

  

Vascular invasion

Yes

38

46

0.004

61

23

0.884

 

No

138

78

160

56

  

Encapsulation

Yes

89

68

0.483

114

43

0.695

 

No

87

56

107

36

  

Number

Single

155

108

0.859

196

67

0.425

 

Multiple

21

16

25

12

  

Size(cm)

≤5

122

72

0.50

145

49

0.585

 

>5

54

52

76

30

  

Differentiation

I-II

128

92

0.793

166

54

0.299

 

III-IV

48

32

55

25

  

TNM stage

I

129

73

0.012

150

52

0.780

 

II-III

47

51

71

27

  
  1. IL-17RE: interleukin-17receptor E; AFP: alpha fetoprotein; ALT, alanine aminotransferase; TNM, tumor-node-metastasis.