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Table 2 Prognostic factors for survival and recurrence

From: High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

Factor

OS

TTR

 

Univeriate

Multivariate

Univeriate

Multivariate

 

P

HR (95% CI)

P

P

HR (95% CI)

P

AFP(ng/ml) (≤20 v >20)

0.022

 

NS

0.003

1.482(1.030-2.132)

0.034

Tumor number (single v multiple)

<0.001

2.803(1.616-4.864)

<0.001

0.011

1.964(1.395-2.766)

0.001

Vascular invasion (yes v no)

<0.001

1.571(1.027-2.401)

0.037

<0.001

 

NS

Tumor size(cm) (≤5.0 v >5.0)

<0.001

2.552(1.671-3.897)

<0.001

<0.001

1.964(1.395-2.766)

<0.001

TNM stage (I v II- III)

<0.001

1.891(1.223-2.926)

0.004

0.001

1.564(1.092-2.240)

0.015

Peritumoral density (low v high) IL-17RE

<0.001

2.172(1.404-3.361)

<0.001

<0.001

1.721(1.222-2.425)

0.002

Intratumoral density (low v high)

IL-17RE

<0.001

 

NS

<0.001

 

NS

Il-17

0.016

 

NS

<0.001

 

NS

Combination of IL-17RE &IL-17

<0.001

1.569(1.315-1.873)

<0.001

<0.001

1.433(1.234-1.663)

<0.001

  1. Univeriate analysis: Kaplan-Meier method; multivariate analysis: Cox proportional hazards regression model.
  2. Abbreviations: OS, overall survival; TTR, time to recurrence; HR, Hazard Ratio; CI, confidence interval; AFP, alpha fetoprotein; TNM, tumor-node-metastasis;IL-17RE, interleukin-17receptor E; NA, not adopted; NS, not significant.