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Table 2 Prognostic factors for survival and recurrence

From: High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

Factor OS TTR
  Univeriate Multivariate Univeriate Multivariate
  P HR (95% CI) P P HR (95% CI) P
AFP(ng/ml) (≤20 v >20) 0.022   NS 0.003 1.482(1.030-2.132) 0.034
Tumor number (single v multiple) <0.001 2.803(1.616-4.864) <0.001 0.011 1.964(1.395-2.766) 0.001
Vascular invasion (yes v no) <0.001 1.571(1.027-2.401) 0.037 <0.001   NS
Tumor size(cm) (≤5.0 v >5.0) <0.001 2.552(1.671-3.897) <0.001 <0.001 1.964(1.395-2.766) <0.001
TNM stage (I v II- III) <0.001 1.891(1.223-2.926) 0.004 0.001 1.564(1.092-2.240) 0.015
Peritumoral density (low v high) IL-17RE <0.001 2.172(1.404-3.361) <0.001 <0.001 1.721(1.222-2.425) 0.002
Intratumoral density (low v high)
IL-17RE <0.001   NS <0.001   NS
Il-17 0.016   NS <0.001   NS
Combination of IL-17RE &IL-17 <0.001 1.569(1.315-1.873) <0.001 <0.001 1.433(1.234-1.663) <0.001
  1. Univeriate analysis: Kaplan-Meier method; multivariate analysis: Cox proportional hazards regression model.
  2. Abbreviations: OS, overall survival; TTR, time to recurrence; HR, Hazard Ratio; CI, confidence interval; AFP, alpha fetoprotein; TNM, tumor-node-metastasis;IL-17RE, interleukin-17receptor E; NA, not adopted; NS, not significant.