From: High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma
Factor | OS | TTR | ||||
---|---|---|---|---|---|---|
 | Univeriate | Multivariate | Univeriate | Multivariate | ||
 | P | HR (95% CI) | P | P | HR (95% CI) | P |
AFP(ng/ml) (≤20 v >20) | 0.022 |  | NS | 0.003 | 1.482(1.030-2.132) | 0.034 |
Tumor number (single v multiple) | <0.001 | 2.803(1.616-4.864) | <0.001 | 0.011 | 1.964(1.395-2.766) | 0.001 |
Vascular invasion (yes v no) | <0.001 | 1.571(1.027-2.401) | 0.037 | <0.001 | Â | NS |
Tumor size(cm) (≤5.0 v >5.0) | <0.001 | 2.552(1.671-3.897) | <0.001 | <0.001 | 1.964(1.395-2.766) | <0.001 |
TNM stage (I v II- III) | <0.001 | 1.891(1.223-2.926) | 0.004 | 0.001 | 1.564(1.092-2.240) | 0.015 |
Peritumoral density (low v high) IL-17RE | <0.001 | 2.172(1.404-3.361) | <0.001 | <0.001 | 1.721(1.222-2.425) | 0.002 |
Intratumoral density (low v high) | ||||||
IL-17RE | <0.001 | Â | NS | <0.001 | Â | NS |
Il-17 | 0.016 | Â | NS | <0.001 | Â | NS |
Combination of IL-17RE &IL-17 | <0.001 | 1.569(1.315-1.873) | <0.001 | <0.001 | 1.433(1.234-1.663) | <0.001 |