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Table 3 Prognostic factors for early and late recurrence

From: High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

Factor Early recurrence Late recurrence
  Univeriate Multivariate Univeriate Multivariate
  P HR (95% CI) P P HR (95% CI) P
AFP(ng/ml)(≤20 v >20) 0.018 1.457(1.012-2.098) 0.043 NS   NA
Tumor size(cm) (≤5.0 v >5.0) <0.001 1.799(1.272-2.544) 0.001 NS   NA
Vascular invasion(yes v no) <0.001 1.472(1.032-2.101) 0.033 NS   NA
TNM stage (I v II- III) 0.001 1.423(1.003-2.020) 0.048 NS   NA
Peritumoral density (low v high) IL-17RE <0.001 1.604(1.129-2.280) 0.008 0.001 2.148(1.158-3.986) 0.015
Intratumoral density (low v high)
IL-17RE 0.001   NS 0.007   NS
Il-17 0.004   NS 0.034   NS
Combination of IL-17RE &IL-17 <0.001 1.430(1.227-1.666) <0.001 <0.001 1.458(1.093-1.947) 0.010
  1. Univeriate analysis: Kaplan-Meier method; multivariate analysis: Cox proportional hazards regression model.
  2. Abbreviations: HR, Hazard Ratio; CI, confidence interval; AFP, alpha fetoprotein; TNM, tumor-node-metastasis;IL-17(RE), interleukin-17(receptor E); NA, not adopted; NS, not significant.