Conventional fractionation | Hypofractionation | ||||||
---|---|---|---|---|---|---|---|
Organ | Parameter | DIBH | FB | p-value | DIBH | FB | p-value |
Heart | Dmax (Gy)(*) | 5.00 | 29.19 | 0.0015 | 3.85 | 24.75 | 0.0025 |
(2.00 – 10.00) | (5.00 – 52.00) | (1.00 – 8.00) | (3.00 – 46.00) | ||||
Dmean (Gy) | 1.24 | 1.68 | 0.0106 | 0.84 | 1.14 | 0.0106 | |
(1.03 – 1.43) | (1.29 – 2.48) | (0.70 – 0.97) | (0.87 – 1.68) | ||||
V20(**) (%) | 0.00 | 0.39 | 0.1574 | 0.00 | 0.33 | 0.1644 | |
(0.00 -0.00) | (0.00 -1.61) | (0.00-0.00) | (0.00 – 1.40) | ||||
V40(**) (%) | 0.00 | 0.16 | 0.1719 | 0.00 | 0.07 | 0.1708 | |
(0.00 -0.00) | (0.00 – 0.70) | (0.00-0.00) | (0.00 -3.00) | ||||
LAD | Dmax (Gy)(*) | 4.25 | 19.62 | 0.0488 | 3.10 | 16.75 | 0.0479 |
(2.00 – 11.00) | (3.00 – 52.00) | (1.00 – 8.00) | (2.00 – 46.00) | ||||
Dmean (Gy) | 2.74 | 9.01 | 0.0914 | 1.86 | 6.12 | 0.9140 | |
(0.80 – 7.55) | (1.45 – 28.05) | (0.54 – 5.13) | (0.99 - 19.07) |