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Figure 1 | Journal of Experimental & Clinical Cancer Research

Figure 1

From: Early-onset colorectal cancer patients without family history are “at very low risk” for lynch syndrome

Figure 1

ROC curve analysis of molecular screening tests. The two ROC curves represent the diagnostic accuracy of Microsatellite Instability analysis (MSI) and Immunoistochemistry (IHC) to identify and select MMR deficient early onset colorectal cancer patients for mutational analysis. Accuracy is measured by the Area Under the Curve (AUC) and is significantly higher in MSI than IHC (AUC 0.97 vs 0.80, p = 0.001).

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