Table 2 Safety profiles of TKI
Small molecule TKI | CNS | Nerve disorders | Eye disorders | Heart disorders | Lung airways disorders | Thyroid disorders | Liver, Bile disorders |
|---|---|---|---|---|---|---|---|
Bosutinib | XX | XX | XX | XX | |||
Dasatinib | X | XX | XX | XX | XX | X | |
Erlotinib | X | XX | XX | XX | X | ||
Gefitinib | XX | XX | XX | ||||
Imatinib | X | XX | XX | X | XX | X | XX |
Lapatinib | X | XX | X | XX | XX | ||
Nilotinib | X | XX | XX | XX | XX | XX | |
Pazopanib | XX | XX | X | XX | XX | XX | |
Ponatinib | XX | XX | XX | XX | XX | ||
Sorafenib | X | XX | X | X | X | ||
Sunitinib | X | XX | XX | X | XX | XX | X |
Small molecule TKI | Gastrointestinal disorders | Renal disorders | Musculoskeletal and bone disorders | Blood and lymphatic system | Vascular disorders | Skin disorders | CMR |
Bosutinib | XX | XX | XX | XX | XX | ||
Dasatinib | XX | X | X | XX | XX | XX | XX |
Erlotinib | XX | XX | X | XX | XX | ||
Gefitinib | XX | XX | XX | XX | XX | ||
Imatinib | XX | X | XX | XX | X | XX | XX |
Lapatinib | XX | XX | XX | XX | XX | ||
Nilotinib | X | X | X | XX | X | XX | XX |
Pazopanib | XX | XX | XX | XX | XX | XX | XX |
Ponatinib | XX | XX | XX | XX | XX | ||
Sorafenib | X | X | X | XX | XX | XX | XX |
Sunitinib | XX | XX | XX | XX | XX | XX | XX |