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Figure 4 | Journal of Experimental & Clinical Cancer Research

Figure 4

From: CD45RA-Foxp3high but not CD45RA+Foxp3low suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression

Figure 4

Percentage of Treg subsets in HNSCC patient subgroups. (A) Flow dot plots of Tregs (Foxp3low and Foxp3high Tregs) (top) and each Treg subset (I: CD45RA+Foxp3low Tregs; II: CD45RA-Foxp3high Tregs; III: CD45RA-Foxp3lowCD4+ T cells) (bottom) for one representative HD and patients with HPSCC, NPSCC, OPSCC, and LSCC. (B) Percentage (means ± SD) of Tregs and each Treg subset in HNSCC patient subgroups or HD. (C) Different proportions (means) of each Treg subset in HNSCC patient subgroups are presented. HD: healthy donors. OCSCC: oral squamous cell carcinoma. HPSCC: hypopharyngeal squamous cell carcinoma. NPSCC: nasopharyngeal squamous cell carcinoma. OPSCC: oropharyngeal squamous cell carcinoma. LSCC: laryngeal squanmous cell carcinoma. Statistical comparisons were performed using the Kruskal–Wallis test.

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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