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Table 2 Relationship between Treg subsets and tumor progression

From: CD45RA-Foxp3high but not CD45RA+Foxp3low suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression

 

CD45RA-Foxp3high

P

CD45RA+Foxp3low

P

CD45RA-Foxp3low

P

Tregs (%)

Tregs (%)

CD4+T cells (%)

T 1–2

1.83 ± 0.82

 

0.54 ± 0.28

 

4.73 ± 1.49

 

T 3–4

2.81 ± 0.89

<0.0001

0.52 ± 0.18

0.834

6.26 ± 1.39

<0.0001

N 0

1.81 ± 0.65

 

0.55 ± 0.17

 

4.93 ± 1.36

 

N +

2.92 ± 1.03

<0.0001

0.50 ± 0.17

0.556

6.07 ± 1.81

<0.0001

  1. Statistical comparisons were performed using the Mann–Whitney U-test.