Detection of AQP3, E-cadherin, and vimentin expression in GC tissue and adjacent normal tissue by IHC. Strong AQP3 immunoreactivity was identified in poorly differentiated adenocarcinomas. E-cadherin expression was observed in normal gastric glands but not in GC tissue. Vimentin expression was not seen in normal tissue but was observed in GC tissue (red arrows). Original magnification, ×400.