Figure 1

Data Sets and Description of Probes with Corresponding Transcripts. A) Transcriptome data sets included in analysis with GSE Series Number as identified on GEO. Platform used, colon tissue type studied, numbers of tissues included, and clinical endpoints are listed. B) TLR4 Gene and Transcripts. Assembly of known TLR4 gene and mRNA transcripts using University of California at Santa Clara Genome Browser. The size of the transcript identified by the individual Affymetrix probes varies and we have denoted them as follows: v1552798aat (Short Probe), v232068sat (Long Probe 1), v224341xat (Long Probe 2), and v221060sat (Medium Probe). C) TLR4 Transcript Table. Description of known transcript variants by length of sequence and protein products where applicable. Complementary probes by platform manufacturer and antibodies for IHC are detailed. This table was adapted from Ensembl Genome Browser.