Multiple functions of hypoxia-regulated miR-210 in cancer

Table 3 Studies investigating diagnostic value of miR-210

First author	Publication year	Types of cancer	Types of sample	Negative controls	Sensitivity	Specificity
Wang [81]	2009	Pancreatic cancer	plasma	Healthy controls	53%	78%
Xing [86]	2010	Squamous cell LC	sputum	Healthy controls	58%	79%
Shen [94]	2011	Lung cancer	plasma	Benign SPNs	56%	73%
Tan [95]	2011	Squamous cell LC	tissue	Normal lung tissue	Not provided	Not provided
Ren [96]	2012	Pancreatic cancer	stool	Healthy controls	85%	67%
Li [97]	2013	NSCLC	sputum	Healthy controls	Not provided	Not provided
Li [98]	2013	NSCLC	serum	Healthy controls	79%	74%
Zhao [99]	2013	Renal cancer	serum	Healthy controls	81%	79%
Iwamoto [100]	2014	Renal cancer	serum	Healthy controls	65%	83%

Abbreviations: LC lung cancer, NSCLC non-small cell lung cancer, SPN solitary pulmonary nodule.

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