Table 2 Relation between LRFS, EZH2 and clinicopathologic factors in patients who received radiation
Prognostic factors | Number of patients/number of deaths | 5-year LRFS (95% CI) | P value |
|---|---|---|---|
Age of diagnosis (N = 62) | |||
≥ 45 | 40/12 | 72.7 (54.8 – 84.8) | 0.43 |
< 45 | 22/7 | 60.9 (33.9 – 79.6) | |
Race (N = 59) | |||
Non-Hispanic White | 48/13 | 74.3 (58.4 – 85.1) | 0.36 |
All others | 11/4 | 56.1 (19.5 – 81.5) | |
Lymph node status (N = 60) | |||
Negative | 7/2 | 83.3 (27.3 – 97.4) | 0.79 |
Positive | 53/16 | 67.3 (51.3 – 79.2) | |
Histologic type (N = 62) | |||
Ductal | 54/17 | 68.7 (53.2 – 80.1) | 0.72 |
Others | 8/2 | 75.0 (31.5 – 93.1) | |
Lymphovascular invasion (N = 56) | |||
No | 9/0 | 100 | 0.07 |
Yes | 47/16 | 66.8 (48.9 – 78.5) | |
ER expression (N = 61) | |||
Negative | 34/16 | 44.4 (24.1 – 62.9) | 0.001 |
Positive | 27/3 | 92.3 (72.6 – 98.0) | |
PR expression (N = 61) | |||
Negative | 42/16 | 58.4 (39.9 – 73.0) | 0.025 |
Positive | 19/3 | 88.2 (60.2 – 96.9) | |
HER2 expression (N = 61) | |||
Negative | 39/13 | 68.5 (49.9 – 81.2) | 0.81 |
Positive | 22/6 | 70.0 (39.1 – 84.3) | |
Triple-negative status (N = 61) | |||
No | 45/9 | 82.6 (66.6 – 91.4) | 0.0001 |
Yes | 16/10 | 25.7 ( 6.4 – 51.0) | |
Radiation type (N = 62) | |||
Postoperative | 55/17 | 69.4 (54.0 – 80.5) | 0.73 |
Preoperative | 7/2 | 64.3 (15.2 – 90.2) | |
BID radiation (N = 48) | |||
No | 10/3 | 80.0 (40.9 – 94.6) | 0.21 |
Yes | 38/14 | 58.0 ( 38.9 – 73.0) | |
EZH2 (N = 62) | |||
No | 17/1 | 92.8 (59.1 – 98.9) | 0.01 |
Yes | 45/18 | 59.2 (41.5 – 73.1) | |