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Table 2 Association of LKB1 immunoreactivity with human breast tumor stage

From: Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion

Clincal stage

Negative <25%

Weak 25%-50%

Moderate 50%-75%

Strong >75%

Score

P value

Stage I

 

5(31)

8(50)

3(19)

30

—

Stage II

1(3)

19(51)

13(36)

4(10)

57

0.0021

Stage III

4(19)

6(29)

9(42)

2(10)

30

0.0006

  1. Fisher’s exact test was performed to determine the association of LKB1 immunoreactivity with stage I, stage II or stage III breast cancer.