Figure 5
From: Reciprocal regulation of PCGEM1 and miR-145promote proliferation of LNCaP prostate cancer cells
Effect of siRNA PCGEM1/PmiR-145 on cell migration. After 48 h, migrated and invasion cells were fixed, stained, and counted. siRNA PCGEM1 and PmiR-145 significantly decreased LNCaP cell migration and invasion and have no effcets on RWPE-1 cell migration. A: a Transwell migration assay was done on LNCaP cells with siRNA PCGEM1 and PmiR-145. Pâ–³* < 0.05 vs control and NC group. B: a Transwell migration assay was done on LNCaP cells with siRNA PCGEM1 and PmiR-145. Pâ–³* > 0.05 vs control and NC group. C: a Transwell invasion assay was done on LNCaP cells with siRNA PCGEM1 and PmiR-145. Pâ–³* < 0.05 vs control and NC group. D: a Transwell invasion assay was done on LNCaP cells with siRNA PCGEM1 and PmiR-145. Pâ–³* > 0.05 vs control and NC group 1: Control group; 2: Negative group: 3: siRNA PCGEM1 group. 4. PmiR-145 group.