Figure 4

Genotype frequencies of SNP16 (rs324148) and SNP18 (rs9394992) in AML patients and healthy control, and their impact on the mRNA expression of SLC29A1. a, genotype frequencies of SNP16 (rs324148) in remission and relapsed patients, and in healthy control. Frequency of genotype CC was higher in relapsed patients than those of CT and TT (P = 0.04); b, genotype frequencies of SNP18 (rs9394992) in remission and relapsed patients, and in healthy control. Frequencies of genotype CT and TT were higher in relapsed patients than those of CC (P = 0.0004). No difference of genotype frequencies of both SNPs was observed between healthy control and remission patients. c, relative mRNA expression of SLC29A1 in patients with different genotypes of SNP16 and SNP18 by quantitative real time PCR, β-actin was used as an internal control. *# + $^ indicated statistically significant (P < 0.05).