Journal of Experimental & Clinical Cancer Research

Table 1 Relationship between expression of CXCR4 and clinicopathological features in IHCC

From: Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway

	CXCR4					χ²	Pvalue
	Case	High		Low
	n	n	%	n	%
Total	122	60	50.8	62	49.2
Sex						0.688	0.447
Male	81	42	51.9	39	48.1
Female	41	18	43.9	23	56.1
Age						1.625	0.254
≥60	80	36	45	44	55
<60	42	24	57.1	18	42.9
Degree of Differentiation						3.673	0.155
Well	16	5	31.3	11	68.7
Moderate	69	33	47.8	36	52.2
Poorly	37	22	59.4	15	40.6
Tumor size						0.265	0.709
<=4.0 cm	46	24	52.1	22	47.9
>4.0 cm	76	36	47.4	40	52.6
Vascular invasion						12.022	0.001
Present	66	42	63.6	24	36.4
Absent	56	18	32.1	38	67.9
CA199						6.664	0.011
≤35KU/L	53	19	34.6	34	65.4
>35KU/L	69	41	60	28	40
Lymph node metastasis						25.231	<0.001
No	47	10	21.3	37	78.7
Yes	75	50	66.7	25	33.3
TNM stage						20.443	<0.001
I and II	22	3	13.6	19	86.4
III	57	26	45.6	31	54.4
IV	43	31	72.1	12	27.9
T stage						15.937	<0.001
T1-T2	48	17	35.4	31	64.6
T3	34	13	32.4	21	67.6
T4	40	30	75	10	25

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ISSN: 1756-9966

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