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Table 1 Relationship between expression of CXCR4 and clinicopathological features in IHCC

From: Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway

  CXCR4 χ2 Pvalue
  Case High Low
  n n % n %
Total 122 60 50.8 62 49.2   
Sex       0.688 0.447
 Male 81 42 51.9 39 48.1   
 Female 41 18 43.9 23 56.1   
Age       1.625 0.254
 ≥60 80 36 45 44 55   
 <60 42 24 57.1 18 42.9   
Degree of Differentiation       3.673 0.155
 Well 16 5 31.3 11 68.7   
 Moderate 69 33 47.8 36 52.2   
 Poorly 37 22 59.4 15 40.6   
Tumor size       0.265 0.709
 <=4.0 cm 46 24 52.1 22 47.9   
 >4.0 cm 76 36 47.4 40 52.6   
Vascular invasion       12.022 0.001
 Present 66 42 63.6 24 36.4   
 Absent 56 18 32.1 38 67.9   
CA199       6.664 0.011
 ≤35KU/L 53 19 34.6 34 65.4   
 >35KU/L 69 41 60 28 40   
Lymph node metastasis       25.231 <0.001
 No 47 10 21.3 37 78.7   
 Yes 75 50 66.7 25 33.3   
TNM stage       20.443 <0.001
 I and II 22 3 13.6 19 86.4   
 III 57 26 45.6 31 54.4   
 IV 43 31 72.1 12 27.9   
T stage       15.937 <0.001
 T1-T2 48 17 35.4 31 64.6   
 T3 34 13 32.4 21 67.6   
 T4 40 30 75 10 25