| | |
Tumor tissue
|
Plasma
|
Total
|
|---|
|
Assay
|
KRASstatus
|
(n = 416)
|
(n = 242)
|
(n = 658)
|
|---|
| |
Wild type
|
260 (63)
|
201 (83)
|
461 (70)
|
| |
Mutated
|
156 (38)
|
41 (17)
|
197* (30)
|
| |
Codon 12
|
118 (28)
|
30 (12)
|
148 (22)
|
|
Direct sequencing
|
12 D
|
50
|
13
|
63
|
| |
12 V
|
39
|
10
|
49
|
| |
Other
|
29
|
7
|
36
|
| |
Codon 13
|
38 (9)
|
11 (5)
|
49 (8)
|
| |
Wild type
|
221 (53)
|
166 (69)
|
387 (59)
|
| |
Mutated
|
195 (47)
|
76 (31)
|
271* (41)
|
| |
Codon 12
|
133 (32)
|
56 (23)
|
189 (29)
|
|
PNA-PCR
|
12 D
|
57
|
26
|
83
|
| |
12 V
|
46
|
17
|
63
|
| |
Other
|
30
|
13
|
43
|
| |
Codon 13
|
62 (15)
|
20 (8)
|
82 (12)
|
- Data expressed as n (%).
- *p < 0.001.PNA-PCR, peptide-nucleic-acid-mediated polymerase chain reaction clamping.
