Figure 2

IC 50 values for standard drugs in the gastric cancer samples divided into two groups based on histological subtype, stage at tumour sampling and patient exposure to chemotherapy prior to sampling. Results are presented as mean values + SE. Number of samples investigated for each drug and sample category was 9 or 10 for intestinal and 5 or 6 for diffuse/signet-ring histology, 11 or 12 for localized and 3 or 4 for metastatic disease, 4 for untreated and 10 – 12 for treated patients. Statistical inference was calculated with Student’s unpaired t-test. *P < 0.05; **P < 0.01; ***P < 0.001 with comparison made within each sample category.