Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia

Table 1 Association of EBF3 expression with clinico-pathological characteristics in 105 pediatric AML samples

Clinical variables	No. of patients	*EBF3* expression (n)		P
Clinical variables	No. of patients	Low	High	P
Gender
Male	42	19	23	0.473
Female	63	33	30
Age (years)
<6	60	29	31	0.778
≥6	45	23	22
Leukocyte (/μl)
>10000	61	32	29	0.479
≤10000	44	20	24
FAB
M1-M6	93	47	46	0.563
M7	12	5	7
Cytogenetics
Favorable	50	23	27	0.502
Intermediate	27	16	11
Unfavorable	28	13	15
MRD
<0.25%	49	28	21	0.114
≥0.25%	56	24	32

ISSN: 1756-9966