|
Analysis
|
Polymorphisms
|
Number of variants
|
Controls n (%)
|
Cases n (%)
|
OR (±95%CI)
|
P
|
|---|
|
Favorable effect
|
p.Arg952Lys ATP7B
|
0
|
52 (15.7)
|
46 (23.78)
|
1 (ref)
| |
|
p.Arg72Pro TP53
|
1
|
162 (48.8)
|
96 (49.5)
|
0.67 (0.42-1.07)
|
0.095
|
| |
2
|
118 (35.5)
|
52 (26.8)
|
0.50 (0.30-0.83)
|
0.008
|
|
Unfavorable effect
|
p.Ile1145 = ABCB1
|
0
|
27 (8.1)
|
3 (1.06)
|
1 (ref)
| |
|
p.Asp1853Asn ATM
|
1
|
95 (28.6)
|
42 (22.3)
|
3.98 (1.13-13.97)
|
0.030
|
|
p.Ser406Ala ATP7B
|
2
|
163 (49.1)
|
104 (55.3)
|
5.74 (1.69-19.50)
|
0.005
|
|
3
|
47 (14.2)
|
39 (20.8)
|
7.47 (2.08-26.85)
|
0.002
|
- Statistically significant analyses are in bold.
