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Table 4 The top 10 enrichment gene ontology terms

From: Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis

Function category

Term

Genes count

k/K (%)

p-Value

Molecular function

KINASE_ACTIVITY

29

0.0786

3.03E-11

 

ION_BINDING

24

0.0879

1.56E-10

 

TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS

30

0.0708

1.81E-10

 

CATION_BINDING

19

0.0892

9.88E-09

 

ENDOPEPTIDASE_ACTIVITY

14

0.1197

2.15E-08

 

PHOSPHOTRANSFERASE_ACTIVITY_ALCOHOL_GROUP_AS_ACCEPTOR

23

0.0689

3.91E-08

 

CALCIUM_ION_BINDING

13

0.125

4.04E-08

 

HYDROLASE_ACTIVITY_ACTING_ON_ESTER_BONDS

20

0.0743

8.62E-08

 

PEPTIDASE_ACTIVITY

17

0.0909

1.10E-07

 

PROTEIN_KINASE_ACTIVITY

20

0.0702

2.20E-07

Biological process

BIOPOLYMER_METABOLIC_PROCESS

83

0.0493

0.00E?+?00

 

SIGNAL_TRANSDUCTION

89

0.0545

0.00E?+?00

 

CELLULAR_MACROMOLECULE_METABOLIC_PROCESS

68

0.0592

0.00E?+?00

 

CELLULAR_PROTEIN_METABOLIC_PROCESS

68

0.06

0.00E?+?00

 

PROTEIN_METABOLIC_PROCESS

76

0.0609

0.00E?+?00

 

SYSTEM_DEVELOPMENT

57

0.0662

0.00E?+?00

 

MULTICELLULAR_ORGANISMAL_DEVELOPMENT

70

0.0667

0.00E?+?00

 

ANATOMICAL_STRUCTURE_DEVELOPMENT

71

0.0701

0.00E?+?00

 

RESPONSE_TO_STRESS

39

0.0768

2.52E-14

 

ORGAN_DEVELOPMENT

40

0.0701

2.29E-13

Cellular function

CYTOPLASM

113

0.0526

0.00E?+?00

 

MEMBRANE_PART

90

0.0539

0.00E?+?00

 

INTRINSIC_TO_MEMBRANE

76

0.0564

0.00E?+?00

 

INTEGRAL_TO_MEMBRANE

76

0.0571

0.00E?+?00

 

ORGANELLE_PART

69

0.0576

0.00E?+?00

 

INTRACELLULAR_ORGANELLE_PART

69

0.0579

0.00E?+?00

 

MEMBRANE

117

0.0587

0.00E?+?00

 

NUCLEUS

84

0.0587

0.00E?+?00

 

PLASMA_MEMBRANE

86

0.0603

0.00E?+?00

 

EXTRACELLULAR_REGION

39

0.0872

3.33E-16

  1. Note: Genes count is number of genes involved. k/K is the ratio of k and K, where k=number of genes in the overlap between this GO term genes and differentially expressed genes, K=total number of genes in the GO term; P value indicates the significance of Genes count.