Table 2 Distribution of PankoMabGEX ™ staining patterns
Mem-PankoMabGEX | Cyt-PankoMabGEX | Double negative | Double positive | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Other | Mem only | Other | Cyt only | No | Yes | No | Yes | ||||||||||||||
n | (%) | n | (%) | p | n | (%) | n | (%) | p | n | (%) | n | (%) | p | n | (%) | n | (%) | p | ||
Histology | |||||||||||||||||||||
NST | 79 | (34.8) | 52 | (22.9) | ns | 122 | (53.7) | 9 | (4.0) | ns | 107 | (47.1) | 24 | (10.6) | 0.008 | 85 | (37.4) | 46 | (20.3) | 0.026 | |
non NST | 57 | (25.1) | 39 | (17.2) | 92 | (40.5) | 4 | (1.8) | 63 | (27.8) | 33 | (14.5) | 76 | (33.5) | 20 | (8.8) | |||||
Grading | |||||||||||||||||||||
G1. G2 | 59 | (37.8) | 44 | (28.2) | ns | 98 | (62.8) | 5 | (3.2) | ns | 79 | (50.6) | 24 | (15.4) | ns | 73 | (46.8) | 30 | (19.2) | ns | |
G3 | 34 | (21.8 | 19 | (12.2) | 50 | (32.1) | 3 | (1.9) | 38 | (24.4) | 15 | (9.6) | 37 | (23.7) | 16 | (10.3) | |||||
pT | |||||||||||||||||||||
pT1 | 82 | (36.4) | 71 | (31.6) | 0.002 | 146 | (64.9) | 7 | (3.1) | ns | 116 | (51.6) | 37 | (16.4) | ns | 115 | (51.1) | 38 | (16.9) | 0.041 | |
pT2-pT4 | 54 | (24.0) | 18 | (8.0) | 66 | (29.3) | 6 | (2.7) | 52 | (23.1) | 20 | (8.9) | 44 | (19.6) | 28 | (12.4) | |||||
pN | |||||||||||||||||||||
pN0 | 62 | (28.8) | 60 | (27.9) | 0.001 | 114 | (53.0) | 8 | (3.7) | ns | 96 | (44.7) | 26 | (12.1) | ns | 94 | (43.7) | 28 | (13.0) | 0.011 | |
pN1-pN3 | 68 | (31.6) | 25 | (11.6) | 88 | (40.9) | 5 | (2.3) | 67 | (31.2) | 26 | (12.1) | 56 | (26.0) | 37 | (17.2) | |||||
CIS | |||||||||||||||||||||
no | 65 | (28.6) | 42 | (18.5) | ns | 102 | (44.9) | 5 | (2.2) | ns | 78 | (34.4) | 29 | (12.8) | ns | 76 | (33.5) | 31 | (13.7) | ns | |
yes | 71 | (31.3) | 49 | (21.6) | 112 | (49.3) | 8 | (3.5) | 92 | (40.5) | 28 | (12.3) | 85 | (37.4) | 35 | (15.4) | |||||
ER | |||||||||||||||||||||
negative | 22 | (10.7) | 8 | (3.9) | ns | 29 | (14.1) | 1 | (0.5) | ns | 17 | (8.3) | 13 | (6.3) | 0.008 | 22 | (10.7) | 8 | (3.9) | ns | |
positive | 99 | (48.3) | 76 | (37.1) | 165 | (80.5) | 10 | (4.9) | 141 | (68.8) | 34 | (16.6) | 120 | (58.5) | 55 | (26.8) | |||||
PR | |||||||||||||||||||||
negative | 43 | (22.6) | 19 | (10.0) | 0.028 | 59 | (31.1) | 3 | (1.6) | ns | 42 | (22.1) | 20 | (10.5) | 0.041 | 42 | (22.1) | 20 | (10.5) | ns | |
positive | 66 | (34.7) | 62 | (32.6) | 121 | (63.7) | 7 | (3.7) | 105 | (55.3) | 23 | (12.1) | 92 | (48.4) | 36 | (18.9) | |||||
Her2 | |||||||||||||||||||||
negative | 90 | (50.0) | 70 | (38.9) | ns | 150 | (83.3) | 10 | (5.6) | ns | 119 | (66.1) | 41 | (22.8) | ns | 121 | (67.2) | 39 | (21.7) | ns | |
positive | 16 | (8.9) | 4 | (2.2) | 18 | (10.0) | 2 | (1.1) | 14 | (7.8) | 6 | (3.3) | 12 | (6.7) | 8 | (4.4) | |||||
age | |||||||||||||||||||||
≤55 y | 57 | (25.2) | 33 | (14.6) | ns | 85 | (37.6) | 5 | (2.2) | ns | 59 | (26.1) | 31 | (13.7) | 0.012 | 69 | (30.5) | 21 | (9.3) | ns | |
>55 y | 79 | (35.0) | 57 | (25.2) | 128 | (56.6) | 8 | (3.5) | 110 | (48.7) | 26 | (11.5) | 91 | (40.3) | 45 | (19.9) | |||||