Figure 4

Effect of FoxM1 on the proliferation and clonogencity of SW620 cells. (A): Down-regulation of FoxM1 expression inhibited the proliferation of SW620 cells compared with the Untreated cells and control-shRNA transfected cells by MTT assay. Figures are curves of SW620 cell growth after transfection for 24, 48 and 72h by MTT assays. (B): Down-regulation of FoxM1 expression reduced the numbers of colonies significantly in SW620 cell line. Cell colonies were stained with 0.1% crystal violet and the colonies containing above 100 cells were counted manually. All data are presented as the means ± SD of three independent experiments.