| |
Score
|
N0/M0
|
N+
|
M+
|
CC
|
|---|
| |
%
|
%
|
%
|
%
|
|---|
|
Tumor center
|
| |
0
|
37
|
33
|
34
|
35
|
|
VEGF-C
|
1
|
34
|
42
|
57
|
65
|
| |
2
|
29
|
25
|
9
|
| |
0
|
39
|
50
|
54
|
48
|
|
VEGF-D
|
1
|
50
|
50
|
33
|
52
|
| |
2
|
11
|
0
|
13
|
|
Tumor budding
|
| |
0
|
35
|
35
|
16
|
29
|
|
VEGF-C
|
1
|
35
|
40
|
74
|
71
|
| |
2
|
30
|
25
|
10
|
| |
0
|
33
|
50
|
52
|
45
|
|
VEGF-D
|
1
|
63
|
50
|
39
|
55
|
| |
2
|
4
|
0
|
9
|
- The intensity of the tumoral staining was scored on a semiquantitative scale from 0 to 2 for the investigated biomolecule (0: no staining, 1: weak staining, 2: strong staining). For the statistical analysis using Fisher’s exact test the examined cases were separated into two groups, characterized by a negative/positive expression for VEGF-C and VEGF-D. The line in the staining intensity column indicates this dichotomization for each biomolecule. There were no significant differences between the groups
