Skip to main content

Table 1 Percentage distribution of the VEGFR-2 ligands VEGF-C and VEGF-D in tumor cells of CC tissue

From: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

  Score N0/M0 N+ M+ CC
  % % % %
Tumor center
  0 37 33 34 35
VEGF-C 1 34 42 57 65
  2 29 25 9
  0 39 50 54 48
VEGF-D 1 50 50 33 52
  2 11 0 13
Tumor budding
  0 35 35 16 29
VEGF-C 1 35 40 74 71
  2 30 25 10
  0 33 50 52 45
VEGF-D 1 63 50 39 55
  2 4 0 9
  1. The intensity of the tumoral staining was scored on a semiquantitative scale from 0 to 2 for the investigated biomolecule (0: no staining, 1: weak staining, 2: strong staining). For the statistical analysis using Fisher’s exact test the examined cases were separated into two groups, characterized by a negative/positive expression for VEGF-C and VEGF-D. The line in the staining intensity column indicates this dichotomization for each biomolecule. There were no significant differences between the groups