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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C

Fig. 1

The effect of curcumin and bicalutamide on growth of prostate cancer cells. a Prostate cancer cells (PC3, DU145 and LNCaP) were treated with increased concentrations of curcumin for up to 72 h to examine the cell viability. b Prostate cancer cells (PC3 and LNCaP) were treated with increased concentrations of bicalutamide for up to 72 h to examine the cell viability c PC3, DU145 and LNCaP cells were treated with curcumin (40 μM) and bicalutamide (30 μM) for 48 h to examine the cell viability. The cell viability was determined using the MTT assay as described in the Materials and Methods section and was expressed as percentage of control in the mean ± SD of three separate experiments. *indicates significant difference as compared to the untreated control group (P < 0.05). **Indicates significant difference from curcumin treated alone (P < 0.05)

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