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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model

Fig. 1

Expression of the pro-angiogenic mediator VEGF is increased in APL transgenic mouse model. a Bone marrow (BM) samples of non-leukemic control hCG-PML-RARα transgenic mice (TM) and hCG-PML-RARα transgenic mice at leukemia diagnosis. b Percentage of VEGF positive cells detected by VEGF-staining by immunohistochemistry and analysis of three microscopic fields (400×) (in brown). ***P < 0.0001 (t-test)

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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