Fig. 1

Plasma levels of miR-24, miR-320a, and miR-423-5p are reduced in patients with CRC. The relative levels of miR-24 (a), miR-320a (b) and miR-423-5p (c) in patients with benign lesions, CRC, IBD, and healthy controls. Numbers are normalized to the reference of cel-miR-39 and shown as log10. The Wilcoxon two-sample tests were performed to examine the difference of three microRNAs between normal controls and colorectal disease groups. (*, p < 0.05; **, p< 0.01; and *** p < 0.001)