Fig. 3
Plasma levels of miR-24, miR-320a, miR-423-5p are better biomarkers for early detection of CRC than currently used CEA, CA19-9. a-f Two-parameter classification is used to detect early stages of CRC. The cut-off value 5.0 ng/mL for CEA is, and 27U/ mL for CA19-9. The data is presented as log2. The cut-off values for miR-24, miR-320a and miR-423-5p are −1.731, −1.006, and −0.854, respectively. The data is calculated from the ROC curve. (g), Detection rates of the three microRNAs CEA, and CA19-9 in a total of 54 patients with early stages of CRC