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Table 2 The diagnosis value between CRC and normal controls

From: Plasma levels of microRNA-24, microRNA-320a, and microRNA-423-5p are potential biomarkers for colorectal carcinoma

Variables

miR-24

miR-320a

miR-423-5p

CEA

CA19-9

Cut-off

−1.731

−1.006

−0.854

5 ng/ml

27U/ml

Sensitivity

78.38 %

92.79 %

91.89 %

40.54 %

36.04 %

Specificity

83.85 %

73.08 %

70.77 %

95.38 %

93.08 %

PPV

80.56 %

74.64 %

72.86 %

88.24 %

81.63 %

NPV

81.95 %

92.23 %

82.88 %

65.26 %

63.02 %

Diagnosis efficiency

81.33 %

82.16 %

80.50 %

70.12 %

66.80 %

  1. PPV positive predictive value, NPV negative predictive value