Fig. 5

The in vitro chemo-sensitization activity by ABC294640. HT-29 cells were treated with 5-FU (5 μM), cisplatin (5 μM), or together with ABC294640 (0.3 μM) for 72 hours, cell growth was tested by MTT assay (a), and cell death was evaluated by LDH release assay (b). Mean values ± SD of three independent experiments were reported. Statistical analysis was performed comparing groups with or without ABC294640 co-treatment. *P < 0.05