Fig. 6

ABC294640 inhibits HT-29 cell growth in vivo. The volumes of HT-29 xenograft tumors in nude mice administrated with ABC294640 (ABC, 5 or 20 mg/kg, p.o., daily) or vehicle (0.375 % Polysorbate-80) control were recorded weekly (n = 10 for each group) (a). Tumor weights (b) and mice body weights (c) at week-6 were also presented. Statistical analysis was performed comparing treatment groups with vehicle control group. *P < 0.05