Fig. 5

Immunohistochemical staining of DDR2 and SNAIL1 in HCC tissues. a The IHC scores of DDR2 in HCC tissues was notably higher than that in the corresponding adjacent no tumorous tissues (NT) (n = 112, P < 0.01). b The IHC scores of SNAIL1 in HCC tissues was notably higher than that in the corresponding adjacent no tumorous tissues (NT) (n = 112, P < 0.01). c In cases of high DDR2 protein expression, there was strong SNAIL1 protein expression in the same tissue section. Similarly, in the case of low DDR2 protein expression, there was no detectable SNAIL1 protein expression in the same tissue section (scale bar: 100 μm). d Linear regression analysis showed a significant positive correlation between ACK1 and p-ACK1 protein expression (P < 0.01)