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Table 1 Correlations between DDR2 expression and clinicopathologic features in HCC

From: DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1

Characteristics n DDR2 expression P value
High Low
Gender     
 Female 25 15 10  
 Male 87 41 46 0.364
Age (year)     
  ≤ 45 29 10 19  
  > 45 83 46 37 0.083
HBsAg statusa     
 Negative 22 7 15  
 Positive 90 49 41 0.095
Cirrhosis     
 No 37 15 22  
 Yes 75 41 34 0.228
AFP (μg/l)b     
  ≤ 400 55 23 32  
  > 400 57 33 24 0.130
Tumor size     
  ≤ 5 cm 37 14 23  
  > 5 cm 75 42 33 0.107
Tumor number     
 Single 86 37 49  
 Multiple 26 19 7 0.013*
Tumor capsule     
 Complete 20 7 13  
 Incomplete 92 49 43 0.217
Vascular invasion     
 No 86 36 50  
 Yes 26 20 6 0.003*
Edmondson grade     
 I/II 64 24 40  
 III/IV 48 32 16 0.004*
TNM stage     
 I/II 67 25 42  
 III/IV 45 31 14 0.002*
  1. a HbsAg hepatitis B surface antigen, b AFP a-fetoprotein, *P < 0.05