Fig. 2From: Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cellsConstitutive phosphorylation status of MEK in NB cells: NB cells were grown in serum containing and serum free media and collected at their exponential growth phase (three days after sub-culture). These cells were lysed in buffer containing protease and phosphatase inhibitors and probed for total and phosphorylated MEK by western blot analysis. Data presented are representative of three separate experimentsBack to article page