Fig. 4

Tivantinib induces G2/M phase arrest and changes the expression of cell cycle related proteins in MHCC97L and Huh7 cells. a MHCC97L and Huh7 cells were treated with tivantinib for 24 h, and then cells were stained with propidium iodide (PI) for flow cytometric analysis. Data were analyzed using Flowjo software and were reported as the mean ± SD. b Changes of the expression of cell cycle related proteins in MHCC97L and Huh7 cells treated with tivantinib for 24 h. *, P < 0.05 vs. the control group