Table 2 Clinical and molecular characteristics of patients without mutations
Patients without APC and MUTYH mutations | ||||
|---|---|---|---|---|
Casea | Age at diagnosis | Phenotype | Family History (transmission) | Additional informations |
GD70 | 43 | AFAP | yes (vertical) | |
GD78 | 35 | Multiple polyposis | yes (vertical) | >10 polyps |
GD80 | 45 | Multiple polyposis | yes (horizontal) | |
GD81 | 36 | AFAP | yes (vertical) | |
GD83 | 36 | FAP | yes (horizontal) | |
GD84 | 32 | FAP | no | desmoids |
GD86 | 17 | FAP | yes (vertical) | 143 microadenomas and 2 polyps |
GD87 | 22 | FAP | no | rectal polyps, desmoids |
GD92 | 58 | AFAP | n.a. | |
GD94 | 65 | AFAP | yes (vertical) | 5 polyps, colon cancer |
GD102 | n.a. | Multiple polyposis | n.a. | cystadenocarcinoma (unknown site) |
GD106 | 50 | Multiple polyposis | n.a. | |
GD107 | 42 | Multiple polyposis | yes (horizontal) | |
GD109 | 52 | Multiple polyposis | no | 36 polyps, colon cancer |
GD112#1 | 37 | FAP | yes (vertical) | colon, gastric, duodenal and rectal polyps |
GD112#2 | 14 | FAP | yes (vertical) | colon and gastric polyps |
GD117 | 63 | Multiple polyposis | yes (horizontal) | 10 polyps, gastric cancer |
GD118 | 71 | AFAP | yes (vertical) | 10 polyps, colon cancer |
GD121 | 41 | AFAP | n.a. | |
GD122 | 59 | Colon cancer | yes (vertical) | |
GD123 | 60 | AFAP | no | colon cancer |
GD140 | 37 | AFAP | no | gastric polyps |
GD146 | 44 | AFAP | no | colon and breast cancer |
GD153 | 47 | AFAP | yes (horizontal) | hyperplastic polyps, colon cancer |
GD154 | 44 | FAP | no | 836 polyps |
GD157 | 53 | FAP | no | colon cancer |
GD158 | 52 | FAP | yes (vertical) | |
GD159 | 26 | FAP | yes (vertical) | rectal cancer |
GD160 | 52 | AFAP | no | 10 polyps |