Fig. 2

Effect of Tpl2 ablation on hepatic mRNA expression of genes related to inflammation (a) and protein phosphorylations of JNK1/2 and ERK1/2 (b). a mRNA expression of genes related to inflammatory and macrophage markers in liver tissue in mice were detected by RT-PCR analysis. Values are expressed as mean ± standard error of the mean (SEM). Actin was used as the control. b Proteins expression of JNK1/2 and ERK1/2 from liver tissue of Tpl2 knockout or wild-type mice were detected by western blotting analysis. Values are mean ± standard error of the mean (SEM). *Comparing with Tpl2 wild type group. Insets: Representative pictures of western blotting analysis