Table 1 Physicochemical characterization of the PUFA nanocapsules using different methods before and after sample fractionation

Formulations

AFM

DLS

Mean

Mean ζ Zeta

AsF4-DLS

AsF4-MALLS

Rg/Rh

mean size

Z-average size

PdI

Potential ± SD (mV)

Z-average

Dg (nm)

(shape factor)

± SD (nm)^a

Dh ± SD (nm)

Dh (nm)

NC PCL

193 ± 28

157 ± 3

0.122

−28.9 ± 1.4

124 ± 9

111 ± 1

1.152

NC PCL-DHA

183 ± 26

161 ± 1

0.113

−29.7 ± 0.7

145 ± 31

116 ± 7

1.032

NC PCL-DHA + Vit E

203 ± 42

179 ± 3

0.089

−20.6 ± 0.7^b

170 ± 25

128 ± 15

0.976

NC PCL-DHA + H2O2

236 ± 59

207 ± 2^{b, c}

0.160

−32.4 ± 1.6^c

144 ± 31

205 ± 13^c

1.838^c

NC PCL-4F4t

194 ± 52

161 ± 3

0.111

−29.5 ± 1.6

120 ± 18

112 ± 9

1.218